Search for Neuroprotective Compounds ―From 4-Methycatechol to Citrus Compounds―

Neuroprotective effect of antioxidant compounds

Neurodegenerative diseases affect millions of individuals worldwide. It has been estimated that the number of patients affected by neurodegenerative diseases such as Alzheimer’s disease (AD), Parkinson’s disease (PD), Huntington’s disease (HD), traumatic brain injury (TBI), stroke and amyotrophic lateral sclerosis (ALS) will increase over time, due to the growing size of the elderly population ...

In vitro neuroprotective activities of compounds from Angelica shikokiana Makino.

Angelica shikokiana is widely marketed in Japan as a dietary food supplement. With a focus on neurodegenerative conditions such as Alzheimer's disease, the aerial part was extracted and through bio-guided fractionation, fifteen compounds [α-glutinol, β-amyrin, kaempferol, luteolin, quercetin, kaempferol-3-O-glucoside, kaempferol-3-O-rutinoside, methyl chlorogenate, chlorogenic acid, hyuganin E,...

Neuroprotective Mechanisms of Natural Polyphenolic Compounds

Natural polyphenols have been reported to exert beneficial effects in preventing cardiovascular diseases but their neuroprotective mechanisms were studied much less. The review is focused on biochemical pathways and molecular neuroprotective mechanisms of natural polyphenols in the brain particularly; of course in close relation to neurophysiological and pathophysiological consequences. This re...

Search for new antifungal compounds from higher plants

The increasing occumnce of opportunistic systemic mycoses associated with the use of immunosuppressive drugs and AIDS has led to new efforts in the search for novel antifungal compounds. At the same time, there is continuing interest in the discovery of antifungal agents which are effective against plant pathogenic fungi. Since the plant kingdom provides a useful source of lead compounds of nov...

Plasma Technology for Removal of Pharmaceutical Compounds from the Environment